[4] Toluca 2-1 Santos Laguna [11] 2022-07-23 22:00
Stadion: Estadio Nemesio Diez Round: 4
Schiedsrichter: Diego Montano Robles Home Manager: Marcos Ignacio Ambriz Away Manager: Eduardo Fentanes
Head to Head
| Mexiko - Liga MX | 2022/01/16 18:00 | Toluca v Santos Laguna | W | 3-1 |
| Mexiko - Liga MX | 2021/10/25 00:06 | Santos Laguna v Toluca | D | 2-2 |
| Mexiko - Liga MX | 2021/04/19 00:00 | Santos Laguna v Toluca | L | 3-1 |
| Mexiko - Liga MX | 2020/09/20 17:00 | Toluca v Santos Laguna | L | 1-2 |
| Mexiko - Liga MX | 2019/11/24 18:00 | Toluca v Santos Laguna | D | 2-2 |
| Mexiko - Liga MX | 2019/02/25 00:06 | Santos Laguna v Toluca | L | 4-0 |
| Mexiko - Liga MX | 2018/09/02 17:00 | Toluca v Santos Laguna | W | 2-1 |
| Mexiko - Liga MX | 2018/05/21 00:00 | Toluca v Santos Laguna | D | 1-1 |
Home History
| Mexiko - Liga MX | 2022/07/14 02:00 | Club America v Toluca | L | 1-0 |
| Mexiko - Liga MX | 2022/07/10 17:00 | Toluca v Atlas | W | 3-2 |
| Mexiko - Liga MX | 2022/07/02 22:00 | Necaxa v Toluca | W | 1-3 |
| Freundschaftsspiele - Vereinsmannschaften weltweit | 2022/05/18 00:30 | Toluca v Bayer Leverkusen | W | 1-0 |
| Mexiko - Liga MX | 2022/05/02 01:06 | Leon v Toluca | D | 4-4 |
| Mexiko - Liga MX | 2022/04/24 17:00 | Toluca v Atlas | L | 2-4 |
| Mexiko - Liga MX | 2022/04/20 02:00 | Toluca v Juarez FC | L | 0-1 |
| Mexiko - Liga MX | 2022/04/17 00:00 | Tigres UANL v Toluca | L | 3-0 |
Away History
| Mexiko - Liga MX | 2022/07/17 00:05 | Santos Laguna v Chivas Guadalajara | D | 1-1 |
| Mexiko - Liga MX | 2022/07/09 02:05 | Puebla v Santos Laguna | L | 1-0 |
| Mexiko - Liga MX | 2022/07/04 00:05 | Santos Laguna v Monterrey | W | 4-3 |
| Freundschaftsspiele - Amerika | 2022/06/19 01:11 | Monterrey v Santos Laguna | W | 0-1 |
| Freundschaftsspiele - Amerika | 2022/06/16 01:30 | Chivas Guadalajara v Santos Laguna | L | 3-1 |
| Mexiko - Liga MX | 2022/05/01 21:00 | Atletico San Luis v Santos Laguna | W | 1-3 |
| Mexiko - Liga MX | 2022/04/25 00:00 | Santos Laguna v Leon | D | 1-1 |
| Mexiko - Liga MX | 2022/04/20 02:00 | Mazatlan FC v Santos Laguna | L | 1-0 |