Stadion: Arthur J. Rooney Athletic Field Round: 1
| NCAAF | 2022/11/19 17:00 | Wagner v Duquesne | W | 0-33 |
| NCAAF | 2022/11/12 17:00 | Duquesne v St.Francis (PA) | L | 14-51 |
| NCAAF | 2022/11/05 16:00 | Sacred Heart v Duquesne | W | 28-35 |
| NCAAF | 2022/10/29 16:00 | LIU Brooklyn v Duquesne | L | 50-48 |
| NCAAF | 2022/10/22 16:00 | Duquesne v Central Connecticut | W | 30-6 |
| NCAAF | 2022/10/08 17:00 | Merrimack v Duquesne | L | 28-21 |
| NCAAF | 2022/10/01 16:00 | Duquesne v Stonehill | L | 20-24 |
| NCAAF | 2022/09/18 04:00 | Duquesne v Hawaii | L | 14-24 |
| NCAAF | 2022/11/12 17:00 | Edinboro Fighting Scots v Lock Haven | W | 26-13 |
| NCAAF | 2022/11/05 17:00 | Slippery Rock v Edinboro Fighting Scots | L | 28-21 |
| NCAAF | 2022/10/29 16:00 | Edinboro Fighting Scots v Seton Hill Griffins | L | 14-45 |
| NCAAF | 2022/10/22 16:00 | Clarion Golden Eagles v Edinboro Fighting Scots | W | 17-47 |
| NCAAF | 2022/10/15 16:00 | Edinboro Fighting Scots v Iup Crimson Hawks | L | 0-41 |
| NCAAF | 2022/10/08 18:00 | Edinboro Fighting Scots v Gannon University Golden Knights | L | 17-35 |
| NCAAF | 2022/10/01 18:00 | Mercyhurst Lakers v Edinboro Fighting Scots | W | 13-16 |
| NCAAF | 2022/09/24 16:00 | California Vulcans v Edinboro Fighting Scots | L | 49-7 |