| NCAAF | 10/26 19:00 | 1 | North Dakota State v South Dakota St | L | 23-16 | |
| NCAAF | 10/19 17:00 | 1 | South Dakota St v Indiana St | W | 42-23 | |
| NCAAF | 10/12 22:00 | 1 | South Dakota St v Youngstown St | W | 38-28 | |
| NCAAF | 10/05 19:00 | 1 | Southern Illinois v South Dakota St | W | 10-28 | |
| NCAAF | 09/21 23:00 | 1 | Southern Utah v South Dakota St | W | 7-43 | |
| NCAAF | 09/14 18:00 | 1 | Drake v South Dakota St | W | 10-38 | |
| NCAAF | 09/07 23:00 | 1 | South Dakota State v LIU Brooklyn | W | 38-3 | |
| NCAAF | 08/30 01:00 | 1 |
South Dakota St
v
Minnesota
|
L | 21-28 | |
| NCAAF FCS | 12/15 01:00 | 2 | South Dakota St v North Dakota St | L | 21-44 | |
| NCAAF | 12/08 19:00 | 3 | Kennesaw State v South Dakota State | W | 17-27 | |
| NCAAF FCS | 12/01 20:00 | 8 | Duquesne v South Dakota St | W | 6-51 | |
| NCAAF FCS | 11/17 20:00 | 1 | South Dakota v South Dakota St | W | 27-49 | |
| NCAAF FCS | 11/10 19:00 | 1 | South Dakota St v Southern Illinois | W | 57-38 | |
| NCAAF FCS | 11/03 19:00 | 1 | Missouri St v South Dakota St | W | 7-59 | |
| NCAAF | 10/27 17:00 | 1 | Illinois State v South Dakota State | W | 28-38 | |
| NCAAF | 10/20 21:00 | 1 | Northern Iowa v South Dakota State | L | 24-9 | |
| NCAAF | 10/13 19:00 | 1 | Youngstown St v South Dakota St | W | 7-36 | |
| NCAAF | 10/06 23:00 | 1 | Indiana St v South Dakota St | W | 51-54 | |
| NCAAF | 09/29 19:30 | 1 | South Dakota St v North Dakota St | L | 17-21 | |
| NCAAF | 09/15 23:00 | 1 |
South Dakota State
v
Arkansas Pine Bluff
|
W | 90-6 | |
| NCAAF | 09/08 23:00 | 1 | Montana State v South Dakota St | W | 14-45 | |
| NCAAF | 09/02 00:00 | 1 |
South Dakota St
v
Iowa State
|
- | Postponed | |
| NCAAF | 12/16 21:30 | 1 | South Dakota St v James Madison U | L | 16-51 | |
| NCAAF | 12/09 20:00 | 1 | New Hampshire v South Dakota St | W | 14-56 | |
| NCAAF | 12/02 20:00 | 1 | Northern Iowa v South Dakota St | W | 22-37 | |
| NCAAF | 11/18 20:00 | 1 | South Dakota v South Dakota State | W | 28-31 | |
| NCAAF | 11/11 20:00 | 1 | South Dakota State v Illinois State | W | 27-24 | |
| NCAAF | 11/04 19:00 | 1 | South Dakota State v North Dakota State | W | 33-21 | |
| NCAAF | 10/28 18:00 | 1 | Western Illinois v South Dakota State | W | 24-52 | |
| NCAAF | 10/21 19:00 | 1 | Missouri St v South Dakota State | W | 30-62 |