| Uruguay - Reserveliga | 03/27 13:30 | - | Defensor Sporting - Reserve v Plaza Colonia - Reserve | W | 2-1 | |
| Uruguay - Reserveliga | 03/14 12:00 | - | Defensor Sporting - Reserve v Liverpool Montevideo - Reserve | W | 3-0 | |
| Uruguay - Reserveliga | 03/06 20:00 | - | Torque - Reserve v Defensor Sporting - Reserve | L | 2-1 | |
| Uruguay - Reserveliga | 02/26 11:30 | - | Defensor Sporting - Reserve v Penarol - Reserve | L | 1-3 | |
| Uruguay - Reserveliga | 12/08 19:00 | - | Defensor Sporting - Reserve v Rentistas - Reserve | D | 1-1 | |
| Uruguay - Reserveliga | 12/05 13:00 | - | Deportivo Maldonado - Reserve v Defensor Sporting - Reserve | L | 2-1 | |
| Uruguay - Reserveliga | 12/01 19:00 | - | Defensor Sporting - Reserve v Danubio - Reserve | L | 0-5 | |
| Uruguay - Reserveliga | 11/24 19:00 | - | Cerrito - Reserve v Defensor Sporting - Reserve | W | 0-1 | |
| Uruguay - Reserveliga | 11/21 19:00 | - | Nacional de Montevideo - Reserve v Defensor Sporting - Reserve | L | 3-1 | |
| Uruguay - Reserveliga | 11/14 12:30 | - | Defensor Sporting - Reserve v Albion FC - Reserve | W | 5-1 | |
| Uruguay - Reserveliga | 11/04 13:00 | - | Fenix - Reserve v Defensor Sporting - Reserve | L | 5-0 | |
| Uruguay - Reserveliga | 10/25 18:00 | - | Defensor Sporting - Reserve v Cerro Largo - Reserve | W | 4-0 | |
| Uruguay - Reserveliga | 10/11 13:00 | - | CA River Plate - Reserve v Defensor Sporting - Reserve | D | 0-0 | |
| Uruguay - Reserveliga | 09/27 13:00 | - | Defensor Sporting - Reserve v Boston River - Reserve | L | 2-3 | |
| Uruguay - Reserveliga | 09/12 18:00 | - | Defensor Sporting - Reserve v Penarol - Reserve | W | 2-1 | |
| Uruguay - Reserveliga | 09/06 14:11 | - | Plaza Colonia - Reserve v Defensor Sporting - Reserve | D | 2-2 | |
| Uruguay - Reserveliga | 08/30 18:00 | - | Defensor Sporting - Reserve v Montevideo Wanderers - Reserve | L | 0-1 | |
| Uruguay - Reserveliga | 07/25 18:00 | - | Liverpool Montevideo - Reserve v Defensor Sporting - Reserve | L | 3-1 | |
| Uruguay - Reserveliga | 06/14 18:00 | - | Rentistas - Reserve v Defensor Sporting - Reserve | L | 3-1 | |
| Uruguay - Reserveliga | 06/06 18:00 | - | Defensor Sporting - Reserve v Deportivo Maldonado - Reserve | D | 1-1 | |
| Uruguay - Reserveliga | 05/31 18:00 | - | Danubio - Reserve v Defensor Sporting - Reserve | W | 0-3 | |
| Uruguay - Reserveliga | 05/26 17:00 | - | Albion FC - Reserve v Defensor Sporting - Reserve | L | 1-0 | |
| Uruguay - Reserveliga | 05/24 17:00 | - | Defensor Sporting - Reserve v Nacional De Football - Reserve | L | 1-3 | |
| Uruguay - Reserveliga | 05/10 18:00 | - | Defensor Sporting - Reserve v Cerrito - Reserve | W | 3-1 | |
| Uruguay - Reserveliga | 05/02 18:00 | - | Defensor Sporting - Reserve v Atletico Fenix Montevideo - Reserve | L | 0-2 | |
| Uruguay - Reserveliga | 04/05 19:00 | - | Defensor Sporting - Reserve v CA River Plate - Reserve | L | 0-2 | |
| Uruguay - Reserveliga | 03/29 19:00 | - | Boston River - Reserve v Defensor Sporting - Reserve | D | 1-1 | |
| Uruguay - Reserveliga | 03/22 18:00 | - | Defensor Sporting - Reserve v Plaza Colonia - Reserve | W | 3-0 | |
| Uruguay - Reserveliga | 03/15 19:30 | - | Montevideo Wanderers - Reserve v Defensor Sporting - Reserve | L | 3-1 | |
| Uruguay - Reserveliga | 03/01 19:30 | - | Defensor Sporting - Reserve v Torque - Reserve | L | 2-3 |